499 Utilization of Diagnostic Sleep Testing Prior to Idiopathic Hypersomnia Diagnosis Among US Adults: A Real-World Claims Analysis

Abstract Introduction A retrospective analysis was conducted to characterize diagnostic sleep testing during the 12 months before diagnosis of idiopathic hypersomnia (IH), a hypersomnolence disorder with no approved treatments. Methods IBM® MarketScan® claims data were analyzed (1/1/14–9/30/19) identify adults newly diagnosed IH, defined as ≥2 an IH code ≥1 day and ≤180 days apart, without ≤12 cohort entry. Demographics, diagnosing physician specialty, (identified via procedure codes for multiple latency test/maintenance wakefulness test [MSLT/MWT], home test, polysomnography) summarized. Analyses performed on patients recorded in any position (“overall IH”) primary (“primary understand effects applying more specific definition IH. Results Of 32,948,986 eligible people, 4,980 (0.015%) identified. Mean age 43 years 67% female; those (n=2,205; 44% overall IH) younger (mean age, 39 years) likely be female (73%). Long time documented 69% group group. The top 3 physicians’ specialties similar IH/primary IH: pulmonology (23%/26%), neurology (14%/16%), internal medicine (11%/10%). Few (9% IH; 7% family practice. Any 53% patients. Polysomnography MSLT/MWT, most frequently used tests, less common (39% 22%) than (48% 32%). Conclusion typically by specialists, outside general medical physicians pulmonologists neurologists both groups. Objective but utilization low regardless diagnosis. Further research is needed investigate clinicians Support (if any) Jazz Pharmaceuticals